(Replying to PARENT post)

One reason to run Emacs in tmux is if you work on remote machines over, e.g. ssh. Emacs in tmux (or screen) lets you detach, log out then log back in and re-attach to the remote session with Emacs still running. That's amazingly handy.
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(Replying to PARENT post)

Another option is tramp[1], which lets you open files remotely (generally via ssh/scp). Not the same thing, but often accomplishes the same goal.

[1] http://www.gnu.org/software/tramp/#Top

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(Replying to PARENT post)

Emacs-server does the same thing.

C-h f server-start

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